The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology.Seven brothers and 5 sisters were living and apparently well. She was a seemingly normal girl until puberty when she developed breasts, masculinized, 17 beta hidroxiesteroide deshidrogenasa failed to menstruate. In a single kindred, 24 affected persons, 17 beta hidroxiesteroide deshidrogenasa in age from a few months to 80 years, were identified. The external genitalia were usually female at birth, although mild to moderate ambiguity was occasionally present. Gonads were palpable in the inguinal canals or labial folds. Although raised as females, all affected persons developed ciclo boldenona y winstrol body habitus and normal male secondary sexual characteristics at puberty.
OMIM Entry - # - BETA HYDROXYSTEROID DEHYDROGENASE III DEFICIENCY
From Wikipedia, the free encyclopedia. The Journal of Biological Chemistry. A convenient purification and demonstration of multiple molecular forms". Brook's Clinical Pediatric Endocrinology. Retrieved 29 April Yen and Jaffe's Reproductive Endocrinology. Principles of Molecular Medicine. HSD17B2 has both anti-estrogenic and anti-androgenic functions. Williams Textbook of Endocrinology. Adult and Pediatric E-Book. Seminars in Reproductive Medicine.
American Journal of Human Genetics. Molecular Aspects of Medicine. Journal of Applied Genetics. Disorders of Sexual Development in Males: Hormones, Brain and Behavior. European Journal of Medicinal Chemistry. Molecular and Cellular Endocrinology. Mevalonate kinase Phosphomevalonate kinase Pyrophosphomevalonate decarboxylase Isopentenyl-diphosphate delta isomerase. Farnesyl-diphosphate farnesyltransferase Squalene monooxygenase Lanosterol synthase.
D-lactate dehydrogenase cytochrome D-lactate dehydrogenase cytochrome c Mannitol dehydrogenase cytochrome. Glucose oxidase L-gulonolactone oxidase Xanthine oxidase. Vitamin K epoxide reductase Vitamin-K-epoxide reductase warfarin-insensitive.
Malate dehydrogenase quinone Quinoprotein glucose dehydrogenase. Allosteric regulation Cooperativity Enzyme inhibitor. EC number Enzyme superfamily Enzyme family List of enzymes.
Molecular and Cellular Biology portal. Retrieved from " https: CS1 German-language sources de Use dmy dates from April Views Read Edit View history.
DBP deficiency , Perrault syndrome , prostate cancer. Prostate, mammary gland, liver, kidney, lung, heart, small intestine, colon, uterus, testis, brain, skeletal muscle, adipose tissue. Ovary, corpus luteum, uterus, placenta, liver, breast, testis, brain, adrenal gland, small intestine, lung, thymus, prostate, adipose tissue, others. Prostate, placenta, kidney, brain, cerebellum, heart, lung, small intestine, ovary, testis, adrenal, stomach.
Liver, small intestine, colon, kidney, heart, brain, placenta, lung, ovary, testis, spleen, thymus, prostate, peripheral blood leukocytes. Liver, pancreas, intestine, kidney, adrenal gland, heart, lung, testis, ovary, placenta, sebaceous gland. Heart, skeletal muscle, liver, kidney, adrenal gland, testis, placenta, cerebellum, pancreas, stomach, small intestine, large intestine, trachea, lung, thyroid, esophagus, prostate, aorta, urinary bladder, spleen, skin, brain, ovary, breast, uterus, vagina.
Liver, bone marrow, lung, ovary, testis, kidney, skeletal muscle, brain, bladder, nasal epithelia. RDH11   . To lanosterol Farnesyl-diphosphate farnesyltransferase Squalene monooxygenase Lanosterol synthase.
To pregnenolone Cholesterol side-chain cleavage.