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Proviron (DHT, Masterlone, Masterolone, Mesterolone) - All about anabolic steroids
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After 90 days of participation comments in the community, you will be automatically approved to create new topics. The Power of DHT self. First off, a basic explanation of DHT Dihydrotestosterone ; it is an androgen male sex hormone , like Testosterone, which rather than promoting the growth of muscle mass directly tissue-acting , it acts via intracellular in the cell mechanisms to increase strength and metabolism.
DHT is not very anabolic, but it is Androgenic, and thus meaning, it promotes masculine characteristics such as a deeper voice, and growth of facial hair, body hair etc 1. DHT has a bad rap, since it has been claimed to cause an enlarged prostate, but if you follow the source, most of the studies saying this are linked to pharmaceutical promotion of their anti-prostate, anti-Male drug, Finasteride Propecia and Dustasteride 2 3.
DHT has also been claimed to cause your hair follicles to become thin, and your hair - subsequently falls out. DHT has been implicated as a factor at most, more studies show that more specifically it is Zinc deficiency AND genetics that provoke male pattern baldness 4 5.
Although Zinc deficiency causes the rise of DHT levels, it also causes increases in prolactin, and estrogen, thus the real problem here could have to do with either of those hormones. But anyway, we got carried away. Let's go on to discuss DHT's effects in the Brain. DHT has pronounced effects on neurochemistry it affects neurotransmitters in the brain.
DHT has been shown to increase circulating epinephrine levels adrenaline , this can cause anxiety in predisposed individuals, however, most of the time, this is not the case, since DHT also increases GABA activity in the brain, which is relaxing 10 11 So in other words, DHT should promote A focused, calm burst of energy, which is what many users of DHT-based steroids, report as the "alpha-male" feeling 13 Dihydrotestosterone increase central and nervous system energy production by increasing not just adrenaline, but cyclic AMP This molecule increase thermogenesis fat-burning and heat production Second to this though, it could indirectly decrease serotonin or serotonin receptors; since DHT antagonizes estrogen activity, and estrogen helps maintain the expression of serotonin receptors in the brain 18 This is also consistent with DHT being shown to stop estrogen induced prolactin release This is part of the reason behind using DHT Gel to treat gynecomasita.
Clearly DHT has anti-depressant effects, since Finasteride causes depression 21 and also based on the above mentioned activity of DHT in the brain. It gives energy, it gives focus, it gives aggression. DHT also decreases glutamate levels and excitory outputs through other mechanisms 26 27 Finally, Dihydrotestosterone, or it's metabolite 3-alpha-Diol; downregulate alpha-adrenergic receptor distribution, leading to more inhibitory adrenergic adrenaline influence 29 30 For those who don't know, adrenaline can activate an 'alpha receptor' - which stimulates the nervous system, vasoconstricting blood vessels and arteries, raising blood pressure, or it can activate a beta-adrenergic receptor, generally vasodilating artieries, but yet, increasing heart contractile force.
However, in a separate study, Testosterone without specificity , had upregulated alphareceptors to protect the heart against ischemia Is this an effect of Testosterone or it's metabolites though. Likely, it doesn't matter, it was probably case coincidental, but may indicate that if blood pressure falls too low, Testosterone can increase it to maintain homeostasis. Interestingly, Alphareceptor activation may increase serotonin activity at the 5-HT1A receptor 34 35 , this is an auto-receptor that ironically seems to possess anxiolytic serotonin-typical effects.
Thus DHT's only pro-aggressive propertly lies in it's adrenaline promoting effect, and not with serotonin. So DHT via multiple pathways increases nervous system strength, DHT increases epinephrine levels, decreases prolactin assuming you have enough dopamine production as well , increases GABA, may decrease serotonin and serotonin receptors. All-round this means DHT has positive effects on your chemistry and nerve cells.
By reducing prolactin, and estrogen, and subsequently serotonin, and also regulating catecholamines, by this, DHT can definitely increase libido, and alleviate sexual anxiety in most individuals by increasing GABA. DHT is key to many of Testosterone's brain benefits. Keep in mind though, despite positive effects on brain chemistry, this still doesn't give an excuse to OD on aromatase inhibitors, likely, because you need a little bit of estrogen not much at all , to promote nNOS neuronal nitric oxide synthase production.
So DHT serves as a great compliment to a little bit of brain estradiol, and a great ratio of DHT to estrogen means optimal sex drive, stamina, charisma and general masculinity. DHT regulates alpha and beta adrenergic receptors. DHT may increase alphareceptor density. Although this may easily be over ridden by the pro-adrenergic effects of DHT. DHT facilitates the release of Epinephrine adrenaline. DHT blocks estrogen-induced prolactin release.
DHT reduces serotonin and serotonin receptors by inhibiting estrogen influence in the Brain. DHT increases nervous system strength and regulates blood pressure. I wonder if there is a link between dht derived steroids and their effect on the brain, due to how dht increases nervous system strength this is why halo, aNavar and anadrol are excellent for strength I wonder if it effects mood. Anavar makes me feel good, halo makes me intense and serious and anadrol is good for in the gym aggression.
Evidence for these occurring due to DHT is circumspect, at best. Zinc deficiency combined with genetics seems to be responsible for all hair line issues, while estro is the demon behind prostate problems.
It imparts focus, aggression, and increases spatial memory. It reduces prolactin moar bonerz, boys! You forgot that it also enhances strength through a different means than just hypertrophy. So particularly useful for a powerlifter looking to get stronger without straying too far from their weight class. Isn't hypertrophy with dht based steroids minimal? If I recall correctly, its mildly anabolic only because it slightly increases igf-1 production.
Yeah that was my understanding. I think they would be particularly useful for athletes dealing with weight class stuff. I think the exception was Anadrol though since it can attach to progesterone receptors. Yeah iirc that's right. I'd like to try anadrol at some point. One of my buddies really liked it. That and tbol are on my list of orals. Is it safe to say these are all reasons why masteron gives you such an awesome "on" feeling?
I was hoping reading through this it sound touch on acne. Mast gives me pretty gnarly acne. I was trying to find out if it was from DHT or the carrier oil. I was told that can be a factor too. Not sure about it though. A bit more than usually but I also increased my test dose and upped deca at the same time. It's gone down after upping my ai dose though.
I convert dht like a mofo, so far prostate and hairline are grrrrreat. I was like 4x top of range on mg test. I love the feeling I get when taking dht based hormones. Honestly when I can afford to and find solid raws I'll probably just add in mast e to whatever I'm running, just for that alone.
In the mean time running the methyl dht I have is pretty awesome. It's liver toxic like other orals. There isn't too much but the east Germans used to use it.
Not sure what you mean by this comment. This article was all about the benefits of dht based drugs. No, I agree, man, it just seems like a lot of the benefits are ancillary and not primarily muscle building. Just wondering why people rave about Mast.