403 ForbiddenNine chronic schizophrenic patients selected from three hospital departments were treated with flupentixol orally and IV and cis Z -flupentixol decanoate in Viscoleo IM flupenthxol a three-phase pharmacokinetic study. Oral administration single and repeated dosage showed a relatively slow absorption with maximum serum lire around 4 h after administration. Intravenous injection indicated multicompartment kinetics for cis Z -flupentixol. The biological half-lives calculated after the different doses were the same, indicating that the pharmacokinetics of cis Z -flupentixol does not differ between single and repeated administration and does not change when flupenthixol decanoate half life higher doses are given. After IM administration maximum serum concentration was flupenthixol decanoate half life between 4 and 10 days in most patients. Calculation of a disappearance flupenthxiol gave very variable results, indicating that the release of the drug from the oil depot is not a monoexponential process. The intramuscular depot had a much lower bioavailability than IV injection, which means flupenthixol decanoate half life steady state has flupenthixol decanoate half life been obtained after 8 weeks of how to boost testosterone levels fast treatment.
Flupenthixol Decanoate Drug Information, Professional
Flupentixol INN , also known as flupenthixol former BAN , marketed under brand names such as Depixol and Fluanxol is a typical antipsychotic drug of the thioxanthene class. It was introduced in by Lundbeck. Flupentixol is not approved for use in the United States.
Flupentixol's main use is as a long-acting injection given once in every two or three weeks to individuals with schizophrenia who have poor compliance with medication and suffer frequent relapses of illness, though it is also commonly given as a tablet.
There however is little evidence to support its use for this indication. Flupentixol is also used in low doses as an antidepressant. Adverse effect incidence     . It should not be used concomitantly with medications known to prolong the QTc interval e.
It should not be given in the following disease states: From Wikipedia, the free encyclopedia. S4 Prescription only CA: Retrieved 20 October Australian Medicines Handbook ed. Russian State Register of Medicinal Products. Retrieved 29 July Cochrane Database of Systematic Reviews.
Experiences with flupenthixol and flupenthixol decanoate". An uncontrolled pilot study with 45 patients". The British Journal of Psychiatry. The Cochrane Database of Systematic Reviews. Lundbeck Australia Pty Ltd. Archived from the original on 8 November British Journal of Pharmacology.
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